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Promotion of Next-generation AI-driven, Data-centric, and Information-circulating Medical Research through an Integrated Framework of Human Resources, AI/DX Technologies, and Institutional Infrastructure

Achievements

2026

Paper

The Molecular and Basic Research Team

Yoshitaka ODA
  1. Severe psoriasis as an immune-related adverse event after long-term atezolizumab therapy for pulmonary large-cell neuroendocrine carcinoma: A case report.Murayama C, Ikezawa Y, Shiiya C, Oda Y, Ikezawa M, Matsunaga A, Tsuji K, Shoji T, Furuta M, Takashima Y, Kitai H, Sakakibara-Konishi J, Konno S.Respiratory medicine case reports, 61;102421DOI: 10.1016/j.rmcr.2026.102421
  2. Virological characteristics of SARS-CoV-2-related coronaviruses dynamically circulating in Southeast AsiaWacharapluesadee S, Saikruang W, Lytras S, Matsumoto K, Uriu K, Hinay A Jr, Guo Z, Rattanatumhi K, Supataragul A, Ninwattana S, Thippamom N, Srisuk T, Maneeorn P, Noradechanon K, Duengkae P, Sirichan N, Kosugi Y, Fujita S, Yo MS, Matsunaga R, Hu B, Du L, Wang L, Tsuda M, Oda Y, Nasser H, Kimura KT, Akasaka H, Asakura H, Nagashima M, Sadamasu K, Yoshimura K, Yamamoto Y, Nagamoto T, Asakura T, Shihoya W, Hashiguchi T, Ikeda T, Tanaka S, Chu H, Tsumoto K, Nureki O; Genotype to Phenotype Japan (G2P-Japan) Consortium; Genotype to Phenotype Asia (G2P-Asia) Consortium; Plianchaisuk A, Putcharoen O, Sato K.Cell, 189(13);4075-4093DOI: 10.1016/j.cell.2026.04.019
  3. Immunological and histopathological features of secondary injury in a long-term mouse model of persistent inflammation, immunosuppression, and catabolism syndromeTsuchida T, Wada T, Mizugaki A, Oda Y, Kayano K, Yamakawa K, Tanaka SShock, 2026
  4. Urothelial carcinoma with loss of SMARCA4 expression with the Site of Origin Identified by Detailed Autopsy InvestigationTakeru Kishinami, Yoshitaka Oda, Zen-ichi Tanei, Takahiro Osawa, Riku Manabe, Ryoko Watanabe, Yuki Hirosato, Yuki Uchida, Akira Nishibe, Kazuhiro Ujihashi, Hiroki, Chiba, Takeru Kuwabara, Koki Ise, Ken Enda, Yusuke Shirai, Hirokazu Sugino, Lei Wang, Masumi Tsuda, Takashige Abe, Shinya TanakaPathology international, 2026
  5. Multimodal Evaluation of Periosteal Versus Collagen Membrane Coverage in Atelocollagen-Associated Autologous Chondrocyte Implantation for Large Knee Cartilage Defects.Kaibara T, Kondo E, Ogawa Y, Matsuoka M, Iwasaki K, Onodera T, Oda Y, Tanei Z, Momma D, Tanaka S, Yasuda K, Yagi T, Iwasaki N.journal of experimental orthopaedics, 2026
  6. Histopathological Comparison of the Parent Artery and the Daughter Sac Reveals Structural Progression in Intracranial Arterial Dolichoectasia.Tatsuta Y, Oda Y, Honjo K, Watanabe T, Osato T, Tanaka S, Nakamura H.BMC Neurology, 2026DOI: 10.1186/s12883-026-05279-5
  7. [A case of IgG4-related pia mater inflammation]Naganuma R, Ando S, Okamoto M, Kishinami T, Oda Y, Miyagishi RRinsho shinkeigaku, 2026DOI: 10.5692/clinicalneurol.cn-002284
Hiroyuki KAMEDA
  1. Effects of AI-based Reconstruction on Image Quality and VBM-based Atrophy Analysis in Accelerated MPRAGEHorie T, Fujima N, Kameda H, Kamishima T, Kudo KMagn Reson Med Sci., 2026
  2. Feasibility and Image Quality Evaluation of Accelerated T2-Weighted and Time-of-Flight MRI Using AI-Assisted Compressed Sensing and Deep ReconstructionTang M, Fujima N, Kameda H, Ikebe Y, Tong Y, Kaji T, Hirata K, and Kudo KJournal of Medical Imaging and Radiation Sciences, 2026
  3. Monitoring of 17O-water dynamics in the human body over one week using direct 17O-MRI: a preliminary studyMoyoko Tomiyasu, Hiromi Sano, Yoshitaka Bito, Takashi Oono, Hiroyuki Kameda, Riwa Kishimoto, Tokuhiko Omatsu, Kohsuke Kudo, Takayuki ObataMRMS, 2026

Imaging and Clinical Research Team

Taku SUGIYAMA
  1. Spetzler-Martin Grade III 脳動静脈奇形に対する外科的摘出術杉山拓，氏原匡樹，栗栖宏多，長内俊也, 中山若樹, 藤村幹脳卒中の外科, 2026
  2. Vessel Wall Enhancement in Brain Arteriovenous Malformations: Associations with Imaging and Histopathological Markers of InstabilityUjihara M, Sugiyama T, Fujima N, Tomaru U, Kurisu K, Osanai T, Fujimura MNeurosurgical Review, 49;405:2026DOI: 10.1007/s10143-026-04336-4
  3. Surgical Video Understanding with Alignment-Preserving Temporal Adaptation and Action Triplet Text AlignmentIkeido T, Togo R, Ogawa T, Sugiyama T, Poudel S, Sugimori H, Tang M, Feng H, Koyano H, Hirata K, Kudo K, Haseyama MBioengineering-Basel, 13;640:2026DOI: 10.3390/bioengineering13060640
  4. Automated Scene Classification and Interpretable Time-Point Estimation for Arteriovenous Malformation Resection Videos Using Deep Learning and a Non-Monotonic Hidden Semi-Markov ModelSugimori H, Sugiyama T, Poudel S, Togo R, Tang M, Feng H, Koyano H, Ujihara M, Hirata K, Ogawa T, Haseyama M, Kudo K, Fujimura MAppl Sci-Basel, 16;7118DOI: 10.3390/app16147118
  5. Impact of Plaque Composition and Its Longitudinal Course on The Recurrence of Ipsilateral Cerebrovascular Events in Symptomatic Mild Carotid Stenosis: A MUSIC StudyKashiwazaki D, Chida K, Yoshida K, Yamada K, Morioka M, Maruichi K, Takagi Y, Moroi J, Miyamoto S, Chin M, Wada K, Sakai N, Izumo T, Nishikawa Y, Mase M, Hosoda K, Takizawa K, Kobayashi E, Kubo M, Fujita A, Sugiyama T, Fujimura M, Yoshioka H, Kinouchi H, Kunieda T, Yoshimura S, Shiokawa Y, Abe H, Kataoka H, Ogasawara K, Uno M, Sasaki M, Kuroda S, the MUSIC Study GroupCerebrovasc Dis, 2026
  6. Collagen Matrix-Assisted Indirect Bypass While Preserving Subcutaneous Soft Tissues in Hemorrhagic Moyamoya Disease: illustrative caseKimata J, Uchino H, Osanai T, Sugiyama T, Fujimura MNMC Case Rep J, 2026
Katsuki EGUCHI
  1. Prevalence and profiles of clinically diagnosed autoimmune cerebellar ataxia in a Japanese nationwide survey.Fujii S, Yaguchi H, Kudo A, Eguchi K, Nomura T, Hayashi H, Tanaka K, Yoneda M, Kimura A, Shimohata T, Takahashi Y, Mizusawa H, Yabe IJ Neurol., 2026;273:215
  2. Nationwide screening identifies an expanded clinical spectrum of anti-KLHL11 antibody-associated neurologic disease in Japan.Pan J, Yaguchi H, Kudo A, Fujii S, Sato H, Yamada K, Uwatoko H, Yang J, Nomura T, Eguchi K, Shirai S, Takahashi-Iwata I, Matsushima M, Okamoto T, Akanuma H, Adachi S, Ishiguro T, Kuwahara H, Tanaka K, Kimura A, Hisahara S, Kanai K, Misawa S, Shimohata T, Takahashi Y, Mizusawa H, Yabe I.J Neurol., 2026;273:321DOI: 10.1007/s00415-026-13816-y
  3. Haplotype analysis of spinocerebellar ataxia type 36 suggests a shared permissive core haplotype across populations.Eguchi K, Miyatake S, Takei A, Yaguchi H, Iida Y, Hamada S, Ito Y, Honma S, Moriwaka F, Wada T, Jono T, Kunii M, Komiya H, Kishida H, Doi H, Tanaka F, Matsumoto N, Yabe I.J Hum Genet., 2026DOI: 10.1038/s10038-026-01489-4
  4. A Novel Presenilin-1 Variant (p.Phe283Val) in Early-Onset Mild Cognitive Impairment With Striatal Amyloid AccumulationIkuko Takahashi-Iwata, Akihiko Kudo, Taichi Nomura, Shintaro Fujii, Katsuki Eguchi, Hisashi Uwatoko, Shinichi Shirai, Masaaki Matsushima, Hiroaki Yaguchi, Takashi Ozaki, Yuichi Nakamura, Takahiro A. Kato, Norikazu Hara, Takeshi Ikeuchi, Ichiro YabeNeurology and Clinical Neuroscience, 2026DOI: 10.1002/ncn3.70174
  5. Mitochondrial Dysfunction in Digenic TBP/STUB1 Spinocerebellar AtaxiaYamada K, Ogata S, Yaguchi H, Fujii S, Nomura T, Kudo A, Eguchi K, Uwatoko H, Shirai S, Takahashi-Iwata I, Matsushima M, Hamanaka K, Miyatake S, Nishino I, Goto YI, Matsumoto N, Yabe I.Mov Disord Clin Pract ., 2026;10:1002/mdc3.70828.DOI: 10.1002/mdc3.70828
  6. Improving Video-Based Prediction of Cerebellar Ataxia Severity Using a Pretrained Deep Learning ModelEguchi K, Yaguchi H, Uwatoko H, Iida Y, Yamada M, Hamada S, Sato K, Honma S, Takei A, Kawashima A, Moriwaka F, Fukazawa T, Togo R, Ogawa T, Haseyama M, Hirata K, Kudo K, Tanaka S, Yabe I.Brain Behav ., 2026;10:e71781DOI: 10.1002/brb3.71781
Ren TOGO
  1. Dual-model weight selection and self-knowledge distillation for medical image classificationAyaka Tsutsumi, Guang Li, Ren Togo, Takahiro Ogawa, Satoshi Kondo, Miki HaseyamaComputers in Biology and Medicine, 2026DOI: 10.1016/j.compbiomed.2026.111510
  2. Personalized federated learning for medical vision-language models via efficient fine-tuning and uncertainty-aware disentanglementHe Zhu, Ren Togo, Takahiro Ogawa, Miki HaseyamaJournal of Biomedical Informatics, 2026DOI: 10.1016/j.jbi.2026.105014

The Big Data Omics Research Team

Kanako C HATANAKA
  1. Extraskeletal Myxoid Chondrosarcoma Mimicking Myoepithelial Tumor.Jiang B, Matsuoka M, Hatanaka KC, Nakazato S, Nakamura H, Nakamura S, Shimizu H, Onodera T, Tanaka S, Hatanaka Y, Iwasaki N.Case Rep Pathol., 2026DOI: 10.1155/crip/2779791
  2. Hokkaido phase II study of photo-immunotherapy combination with ASP-1929 for recurrent or persistent EGFR-positive vulvar, vaginal, and cervical cancers not amenable to further radiotherapy (HICARi study)Asano H, Yamazaki H, Matsumiya H, Yokota I, Okada K, Yamamoto R, Hatanaka KC, Sasajima Y, Nagamine M, Hatanaka Y, Kato F, Takahama J, Tsuboyama T, Watanabe Y, Okita N, Watari HJ Gynecol Oncol., 2026DOI: 10.3802/jgo.2026.37.e126
  3. Feasibility study of photoimmunotherapy combination with ASP-1929 for vulvar, vaginal, and cervical cancerYamamoto R, Asano H, Hatanaka KC, Shinomiya Y, Yamazaki H, Matsumiya H, Nagamine M, Sasajima Y, Hatanaka Y, Watari HJ Gynecol Oncol., 2026DOI: 10.3802/jgo.2026.37.e125
  4. Pathological and molecular characterization of a four-component combined small cell lung carcinoma: a case reportIkezawa Y, Shinomiya Y, Hatanaka KC, Makita K, Nishimura H, Takagi T, Tabata Y, Watanabe M, Konno S, Hatanaka Y, Kawai YTransl Lung Cancer Res., 2026;15:155DOI: 10.21037/tlcr-2026-1-0144
  5. Clinical and Functional Significance of C16orf74 in Extrahepatic CholangiocarcinomaKimura K, Nakamura T, Kushibiki T, Fujii M, Kuraya T, Niwa H, Nakanishi Y, Takeuchi S, Sasaki K, Hatanaka KC, Hatanaka Y, Wada M, Matsui A, Tanaka K, Asano T, Noji T, Tsuchikawa T, Hirano SAnticancer Res., 46;8:251-4265DOI: 10.21873/anticanres.18284
  6. Urinary miR-574-5p as a candidate biomarker for early-stage lung adenocarcinoma: an exploratory case-control studyNagashima R, Aragaki M, Hatanaka KC, Shinomiya Y, Ushijima M, Fujiwara-Kuroda A, Ohtaka K, Shiiya H, Chiba R, Otsuka S, Nakaya T, Omine R, Kuji T, Hatanaka Y, Kato T.Transl Lung Cancer Res., 2026;15:244DOI: 10.21037/tlcr-2026-0600
  7. Feasibility of routine clinical liquid-based cytology for lung cancer compact panel testingShinomiya Y, Hatanaka KC, Okumura A, Nange A, Yamamoto M, Azuma M, Marukawa K, Ishida Y, Shimizu T, Watanabe R, Hashimoto Y, Abiko M, Sato Y, Sakakibara-Konishi J, Kato T, Tanaka S, Hatanaka YCancer Cytopathol., 2026;134:e70135DOI: 10.1002/cncy.70135
Hidenori KITAI
  1. Hierarchical multi-label structuring of Japanese SOAP clinical notes with large language modelsZiheng Zhang, Minghui Tang, Feng Han, Hidenori Kitai, Kenji Hirata, Katsuhiko Ogasawara, Satoshi Konno & Kohsuke Kudoscientific reports, 16;1:27551DOI: 10.1038/s41598-026-58622-8

International Conference

The Molecular and Basic Research Team

Ken MURAMATSU
  1. Basophils exacerbate bullous pemphigoid by promoting natural killer cell-mediated skin inflammation and by regulating dendritic cell accumulation and T cell proliferation in secondary lymphoid organsKawamura T, Muramatsu K, Miyake K, Ito T, Katayama S, Shiiya C, Yoshimoto N, Izumi K, Karasuyama H, Ujiie H55th Annual ESDR Meeting, Heidelberg, Germany, 2026
  2. Construction of HLA-DQA1*05:05/HLA-DQB1*03:01 with Type XVII Collagen Protein Complex for Elucidating the Pathomechanism of DPP-4 Inhibitor-Associated Bullous PemphigoidMuramatsu K, Kurosawa S, Tsuyuki T, Maenaka K, Ujiie HIPPF Scientific Symposium on Pemphigus and Pemphigoid, Lubeck, Germany, 2026
Tsutomu TANAKA
  1. MHC-I transactivator NLRC5 suppressed development of lung cancer with Kras mutation.Tsutomu Tanaka, Sayuri Yoshihama, Suhail Yousuf, Tabasum Sidiq, Yusuke Kasuga, Atsuki Takeishi, Yoshitaka Oda, Steven Cho, Shinya Tanaka, Koichi S Kobayashi44th Sapporo international cancer symposium, Sapporo, Hokkaido, 2026
  2. Dual Epigenetic intervention to enhance the MHC-I-dependent immune response against solid tumors.Alaa Ahmad, Tsutomu Tanaka, An Ning, Xin Sun, Ryota Ouda, Koichi S. Kobayashi.44th Sapporo international cancer symposium, Sapporo, Hokkaido, 2026
  3. IRF1 plays a significant role in NLRC5-dependent MHC-I antigen presentation pathway.Tsutomu Tanaka, Torsten B. Meissner, Saptha Vijayan, Kyoung-Hee Lee, Yuen-Joyce Liu, Isaac Downs, Jason Yeung, Koichi S. Kobayashi.The 24th Awaji International Forum on Infection and Immunity., Sapporo, Hokkaido, 2026
  4. Defining the role of NF-Y in NLRC5-mediated MHC class I gene expression.Zufang Wu, Yuichi Igarashi, Tsutomu Tanaka, Yusuke Kasuga, Koichi KobayashiThe 24th Awaji International Forum on Infection and Immunity., Sapporo, Hokkaido, 2026
  5. Elucidating Sjögren Disease Pathogenesis Using a Novel Lysosome-Associated Membrane Protein 3-Overexpressing ModelTsutomu Tanaka17th International Symposium on Sjögren’s Disease (ISSjD 2026), Paris, French, 2026
Yoshitaka ODA
  1. Pathological Diagnosis of Meningioma Toward WHO CNS6Yoshitaka Oda21st Asian Society for Neuro-Oncology: Pre-ASNO 2026 ASNO-ASONP Joint Education Session in Neuropathology, Ishikawa Ongakudo (Kanazawa), 2026
Hiroyuki KAMEDA
  1. AI in Neuroimaging: From Research to Clinical Practice亀田浩之モンゴル放射線学会2026, ウランバートル, 2026
  2. Dynamic Direct 17O Water MRI of the Rat Brain at Clinical 3T: 3D Radial Acquisition and Denoising StrategiesHiroyuki Kameda, Yuta Urushibata, Yoshitaka Bito, Naoya Kinota, Daisuke Kato, Takaaki Fujii, Kohsuke Kudo2026 ISMRM Workshop on Beyond Protons: Challenges and Advances in X-Nuclei MR, Barcelona, 2026
  3. Other X-Nuclei Imaging (Li, F, K, O)Hiroyuki Kameda2026 ISMRM Workshop on Beyond Protons: Challenges and Advances in X-Nuclei MR, Barcelona, 2026

Imaging and Clinical Research Team

Taku SUGIYAMA
  1. Microsurgical resection for intermediate-grade brain arteriovenous malformationsSugiyama T, Ujihara M, Osanai T, Nakayama N, Fujimura MThe 18th Korea-Japan Joint Conference on Surgery for Cerebral Stroke (KJJC), Osaka, 2026
  2. Age-dependent association between concomitant cilostazol use and delayed ischemic events in clazosentan-treated aneurysmal subarachnoid hemorrhage: A multicenter prospective registrySugiyama T, Nakazaki A, Shimbo D, Ito M, Shimoda Y, Hokari M, Tatezawa R, Ito Y, Gekka M, Uchino H, Fujimura MThe 18th Korea-Japan Joint Conference on Surgery for Cerebral Stroke (KJJC), Osaka, 2026
  3. Surgical Data Science and AI for Advancing Safety Management and Education in Neurosurgery; Data-Driven Analysis of Intraoperative EventsSugiyama TEANS2026 Hamburg, Hamburg, 2026
Ren TOGO
  1. “Enhancing Story Visualization via Subject-Aware Inpainting with SOEDiff”Hideo Kodama, Masaki Yoshida, Ren Togo, Takahiro Ogawa, Miki HaseyamaInternational Workshop on Advanced Image Technology (IWAIT), 2026.
  2. “Similar Video Retrieval for Laparoscopic Cholecystectomy Videos Based on Image and Text Feature Representations with Temporal Context Integration”Taiyo Ikeido, Ren Togo, Takahiro Ogawa, Miki HaseyamaInternational Workshop on Advanced Image Technology (IWAIT), 2026.
  3. “Dual-Model Weight Selection and Wasserstein Knowledge Distillation for Medical Image Classification”Ayaka Tsutsumi, Guang Li, Ren Togo, Takahiro Ogawa, Satoshi Kondo, Miki HaseyamaIFMIA, 2026.
  4. H3GM: HISTORY-GUIDED GLOBAL GEOMETRIC METRIC FOR SINGLE IMAGE TO 3D SCENE GENERATIONYuki Katayama, Ren Togo, Keisuke Maeda, Takahiro Ogawa, Miki HaseyamaIEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), Barcelona (Spain), 2026
  5. CROSS-MODAL SIMILAR VIDEO RETRIEVAL IN LAPAROSCOPIC CHOLECYSTECTOMY VIDEOS CONSIDERING TEMPORAL AND HIERARCHICAL INFORMATIONTaiyo Ikeido, Ren Togo, Takahiro Ogawa, Miki HaseyamaIEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), Barcelona (Spain), 2026
  6. Personalized longitudinal medical report generation via temporally-aware federated adaptationHe Zhu, Ren Togo, Takahiro Ogawa, Kenji Hirata, Minghui Tang, Takaaki Yoshimura, Hiroyuki Sugimori, Noriko Nishioka, Yukie Shimizu, Kohsuke Kudo, Miki HaseyamaThe IEEE/CVF Conference on Computer Vision and Pattern Recognition 2026, Denver, 2026
  7. ADAPTIVE SHARED EXPERTS WITH LORA-BASED MIXTURE OF EXPERTS FOR MULTI-TASK LEARNINGMinghao Yang, Ren Togo, Guang Li, Takahiro Ogawa, Miki HaseyamaIEEE International Conference on Acoustics, Speech, and Signal Processing (ICASSP), Barcelona (Spain), 2026
  8. Reranking-based Analysis on Visual and Textual Query Contribution to Composed Image RetrievalHuaying Zhang, Ren Togo, Takahiro Ogawa, Miki HaseyamaACM International Conference on Multimedia Retrieval (ICMR), Netherlands, 2026
  9. Analysis of model merging for integrating adversarial robustness across diverse datasets in CLIP modelsKoshiro Toishi, Keisuke Maeda, Soichiro Kumano, Ren Togo, Toshihiko Yamasaki, Takahiro Ogawa, Miki HaseyamaIEEE International Conference on Consumer Electronics – Taiwan (ICCE-TW), Taiwan, 2026
  10. Understanding the layer-wise role of text-stream modulation in diffusion transformersHideo Kodama, Masaki Yoshida, Ren Togo, Takahiro Ogawa, Miki HaseyamaIEEE International Conference on Consumer Electronics – Taiwan (ICCE-TW), Taiwan, 2026

The Big Data Omics Research Team

Hidenori KITAI
  1. Identification of TROP2 as an adaptive resistance mechanism in KRAS G12C inhibition and its therapeutic targetingMasahiro Kashima Hidenori Kitai, Yukiko Yoshida, Yuriko Ishida, Yuma Sato, Daisuke Morinaga , Kosuke Tsuji, Shotaro Ito, Kanako C. Hatanaka, Takuma Kobayashi, Yoshiki Shinomiya, Teppei Konishi, Yutaka Hatanaka, Jun Sakakibara-Konishi, Satoshi KonnoAACR（米国癌学会）, アメリカ、サンディエゴ, 2026

Domestic Conference

The Molecular and Basic Research Team

Ken MURAMATSU
  1. 掌蹠に角化を伴った水疱性類天疱瘡の3例九冨友里花、村松　憲、浅田将太、片山　奨、伊東孝政、氏家韻欣、氏家英之第446回日本皮膚科学会北海道地方会，札幌，2026
  2. 病理解剖で閉塞性細気管支炎を確認した腫瘍随伴性天疱瘡の1例田中　諒、村松　憲、上野翔子、氏家韻欣、秋山采慧、遠田　建、古賀浩嗣、氏家英之第446回日本皮膚科学会北海道地方会，札幌，2026
Tsutomu TANAKA
  1. SARS-CoV-2 targets MHC class I antigen presenting pathway for immune evasionPatrick H.N. Kao, Baohui Zhu, Tsutomu Tanaka, Tomokazu Tamura, Takasuke Fukuhara, Koichi S. Kobayashi日本ウイルス学会北海道支部 第59回 夏季シンポジウム，旭川、北海道，2026
  2. A novel regulator of MHC-I and innate immune responseWei Jie Cheah, Gabriel Talaia, Tsutomu Tanaka, Koichi Kobayashi日本ウイルス学会北海道支部 第59回 夏季シンポジウム，旭川、北海道，2026
  3. Nobel NLRC5 binding protein regulate tumor growth by altering expression of MHC-I.Tsutomu Tanaka, Ryota Ouda, Noyuri Zama, Yoshitaka Oda, Xin Sun, Shinya Tanaka, Koichi S Kobayashi第85回日本癌学会，京都，2026
  4. A Therapeutic Strategy Targeting Epigenetic Suppressors to Enhance the MHC-I-Mediated Anti-Tumor Response.Alaa Ahmad, Tsutomu Tanaka, An Ning, Xin Sun, Ryota Ouda, Koichi S Kobayashi第85回日本癌学会，京都，2026
Yoshitaka ODA
  1. SARS-CoV2ハムスター肺炎モデルに対する病理学的解析への人工知能の応用小田義崇、遠田建、王磊、種井善一、平田健司、福原崇介、佐藤佳、津田真寿美、田中伸哉第115回日本病理学会総会，グランドメルキュール札幌大通公園他（札幌市），2026
  2. ハイドロゲル誘導がん幹細胞の研究および病理スコアリングの開発小田義崇第115回日本病理学会総会，グランドメルキュール札幌大通公園他（札幌市），2026

Imaging and Clinical Research Team

Taku SUGIYAMA
  1. 脳動静脈奇形に対する根治手術戦略と合併性評価杉山拓、氏原匡樹、栗栖宏多、長内俊也、藤村幹第35回日本脳神経外科手術と機器学会，徳島，2026
  2. 脳神経外科の術者教育と手術安全のためのAI導入研究杉山拓, 杉森博行, 唐明輝第78回日本産婦人科学会学術講演会，札幌，2026
Katsuki EGUCHI
  1. Video- and AI-based assessment of ataxiaKatsuki Eguchi, Hiroaki Yaguchi, Ichiro Yabe第67回日本神経学会学術大会，横浜，2026
  2. 歩行動画から小脳性運動失調重症度を予測するAIモデルの事前学習による精度改善江口克紀第20回パーキンソン病・運動障害疾患コングレス，函館，2026
Ren TOGO
  1. 出力トークン確率に基づく隠れ状態編集によるMLLMの視覚–知識統合の改善に関する検討佐藤雅也，前田圭介，藤後廉，小川貴弘，長谷山美紀映像情報メディア学会技術報告，札幌，2026
  2. A Note on Re-ranking using Edited Image Query for Composed Image RetrievalHuaying Zhang，Ren Togo，Takahiro Ogawa，Miki Haseyama映像情報メディア学会技術報告，札幌，2026
  3. A Note on Object-Aware Dataset Distillation with Adaptive Patch SelectionLongzhen Li，Guang Li，Ren Togo，Keisuke Maeda，Takahiro Ogawa，Miki Haseyama映像情報メディア学会技術報告，札幌，2026
  4. ラベルノイズ環境におけるNoisy Label LearningとActive Learningの統合に関する検討柏木將希，前田圭介，藤後廉，小川貴弘，長谷山美紀映像情報メディア学会技術報告，札幌，2026
  5. 手術動画を対象としたフェーズ認識性能向上に向けた時系列情報活用の検討 ～ Transformer型時系列エンコーダ導入が認識精度に及ぼす影響の分析 ～池井戸大湧，藤後廉，小川貴弘，長谷山美紀映像情報メディア学会技術報告，札幌，2026
  6. Open-Vocabulary物体検出モデルを導入したオブジェクト中心の3Dシーン評価指標に関する検討内田結子，藤後廉，前田圭介，小川貴弘，長谷山美紀映像情報メディア学会技術報告，札幌，2026
  7. 拡散モデルのトークン制御に基づくストーリー画像生成の一貫性向上に関する検討小玉秀郎，吉田将規，藤後廉，小川貴弘，長谷山美紀映像情報メディア学会技術報告，札幌，2026
  8. ［特別講演］令和6年度橋梁定期点検要領へ対応するためのIn-context Learningに基づく所見生成AIの拡張佐藤雅也，前田圭介，藤後廉，小川貴弘，長谷山美紀映像情報メディア学会技術報告，札幌，2026
  9. 特別講演］映像内の局所領域に着目した動作キャプション生成に基づくタイヤ点検動作認識に関する取組上川恭平，藤後廉，前田圭介，小川貴弘，長谷山美紀映像情報メディア学会技術報告，札幌，2026
  10. ［特別講演］ゴム材料生産過程における因果探索に基づく変数間の関連性分析に関する取組張華瀛，藤後廉，前田圭介，小川貴弘，長谷山美紀映像情報メディア学会技術報告，札幌，2026
  11. ［特別講演］大規模マルチモーダルモデルの潜在表現を用いたインテリアコーディネート画像からのスタイル推定に関する一検討山森諄也，藤後廉，山城輝久，小川貴弘，長谷山美紀映像情報メディア学会技術報告，札幌，2026
  12. 因果的Self-Attentionを用いた逐次推薦モデルにおける残差支配がもたらす最終アイテム依存神崎恵土，櫻井慶悟，藤後廉，小川貴弘，長谷山 美紀第18回データ工学と情報マネジメントに関するフォーラム(DEIM2026)，神戸，2026

Outreach

The Molecular and Basic Research Team

Takanori SHINOTSUKA
  1. 脳の中の“水”を追いかける篠塚 崇徳山脇学園中学校・高等学校（東京都港区）

2025

Paper

Imaging and Clinical Research Team

Ren TOGO
  1. “Privacy-aware continual self-supervised learning on multi-window chest CT for domain shift robustness,”Ren Tasai, Guang Li, Ren Togo, Takahiro Ogawa, Kenji Hirata, Minghui Tang, Takaaki Yoshimura, Hiroyuki Sugimori, Noriko Nishioka, Yukie Shimizu, Kohsuke Kudo, Miki HaseyamaBioengineering, 2025.DOI: 10.3390/bioengineering13010032
  2. “TPSMG: Text-controllable polyphonic symbolic music generation,”Jinlong Zhu, Keigo Sakurai, Ren Togo, Takahiro Ogawa, Miki HaseyamaITE Transactions on Media Technology and Applications, 2025.DOI: 10.3169/mta.14.110
  3. "Deep-learning-based automatic liver segmentation using computed tomography images in dogs"Seungyeon Lee, Genya Shimbo, Nozomu Yokoyama, Kensuke Nakamura, Ren Togo, Takahiro Ogawa, Miki Haseyama and Mitsuyoshi TakiguchiFrontiers in Veterinary Science, 2025.DOI: 10.3389/fvets.2025.1681820

Award

Imaging and Clinical Research Team

Ren TOGO
  1. 若手優秀論文発表賞令和7年度電気・情報関係学会北海道支部連合大会（神崎 恵土, 他)

International Conference

The Molecular and Basic Research Team

Takanori SHINOTSUKA
  1. " Stimulated Raman scattering imaging visualizes the water dynamics in the mouse brain"T. Shinotsuka, Y. Ozeki, M. Yasui, M. NuriyaNeuroscience 2025. (2025).

Imaging and Clinical Research Team

Taku SUGIYAMA
  1. Clinical factors associated with delayed ischemic and non-ischemic adverse events in clazosentan therapy after aneurysmal subarachnoid hemorrhage: A multicenter prospective registrySugiyama T, Hokari M, Shimbo D, Uchino H, Shimoda Y, Okamoto M, Ito Y, Gekka M, Saito H, Yamamoto T, Fujiwara Y, Fujimura MEANS (The European Association of Neurosurgical Societies) 2025 Vienna Congress, Vienna, Austria, 2025
  2. AI-based Video Analysis of Instrument Motion and Tissue Deformation for Microvascular Anastomosis TrainingSugiyama T, Tang M, Sugimori H, Fujimura MEANS (The European Association of Neurosurgical Societies) 2025 Vienna Congress, Vienna, Austria, 2025
Ren TOGO
  1. “MLLM-guided Training-free Spherical Panorama Generation from a Single Image”Yuki Katayama, Ren Togo, Keisuke Maeda, Takahiro Ogawa, Miki HaseyamaACM SIGGRAPH Asia Posters (SIGGRAPH Asia), 2025.
  2. “Lost in the Interface: How Structured UI Complexity Challenges Large Vision Language Models in Games”Xiang Li, Ren Togo, Keisuke Maeda, Takahiro Ogawa, Miki HaseyamaACM SIGGRAPH Asia Technical Communications (SIGGRAPH Asia), 2025.

Domestic Conference

The Molecular and Basic Research Team

Ken MURAMATSU
  1. パンツ型浸潤転移を生じたエクリン汗孔癌の1例浅田 将太，村松 憲，宮本 航大，佐藤 聡真，氏家 英之第444回日本皮膚科学会北海道地方会．札幌，2025/12
  2. 黄色爪症候群の6例渡邊 由佳子，椎谷 千尋，村松 憲，瀬尾 拓志，小住 英之，氏家 英之第444回日本皮膚科学会北海道地方会．札幌，2025/12

Imaging and Clinical Research Team

Taku SUGIYAMA
  1. 根治性を重視した脳動静脈奇形根治手術における安全性評価杉山 拓，栗栖 宏多，氏原 匡樹，長内 俊也，内野 晴登，藤村 幹第84回日本脳神経外科学会学術総会，横浜，2025
Ren TOGO
  1. “ユーザ行動系列エンコーダの周波数特性を考慮した逐次推薦モデルに関する検討,”神崎 恵土，櫻井 慶悟，藤後 廉，小川 貴弘，長谷山 美紀令和7年度電気・情報関係学会北海道支部連合大会 講演論文集, 2025.
  2. “腹腔鏡下胆嚢摘出術動画における時系列表現を考慮した類似動画検索に関する検討,”池井戸 大湧，藤後 廉，小川 貴弘，長谷山 美紀令和7年度電気・情報関係学会北海道支部連合大会 講演論文集, 2025.
  3. “単一画像からの3Dシーン生成における大域的整合性評価指標の提案,”片山 優希，藤後 廉，前田 圭介，小川 貴弘，長谷山 美紀令和7年度電気・情報関係学会北海道支部連合大会 講演論文集, 2025.
  4. “SOEDiffを用いた一貫性のある複数被写体画像生成パイプラインの提案,”小玉 秀郎，吉田 将規，藤後 廉，小川 貴弘，長谷山 美紀令和7年度電気・情報関係学会北海道支部連合大会 講演論文集, 2025.
  5. “推論強化と視覚保持の両立のためのVLMとLLMのモデルマージ手法に関する検討,”三ツ井 智哉，藤後 廉，斉藤 直輝，小川 貴弘，長谷山 美紀令和7年度電気・情報関係学会北海道支部連合大会 講演論文集, 2025.

Invited Lecture

The Molecular and Basic Research Team

Takanori SHINOTSUKA
  1. " Visualization of water dynamics in brain: application of the Stimulated Raman Scattering imaging to the neuroscience"T. ShinotsukaKeio University – Academia Sinica Joint Workshop Multidisciplinary Approach to Living and Active Matter Systems. (2025)

Outreach

The Molecular and Basic Research Team

Takanori SHINOTSUKA
  1. “巨人の肩の上に立つ”篠塚 崇徳山脇学園中学校・高等学校（東京都港区）